Sertindole-Risperidone LA

Sertindole
Type Antipsychotic
Group Atypical AP
links
PubChem 60149
PubMed Sertindole
Kompas (Dutch) Sertindole
Wikipedia Sertindole
Risperidone
long acting
Type Antipsychotic
Group Atypical AP
links
Medscape Risperidone
PubChem 5073
PubMed Risperidone
Kompas (Dutch) Risperidone
Wikipedia Risperidone

Switch medication from Sertindole to Risperidone_LA.

Nietinrijdenbord.png Stop Sertindole
  • Day 1-14: Continue drug at usual dose
  • Day 15-18: approx. 75% of initial dose
  • Day 19-22: approx. 50% of initial dose
  • Day 23-27: approx. 25% of initial dose
  • Day 28: stop
Eenrichtingbord.png Start Risperidone_LA
  • Day 1: Start depot according general dosing advice (Dotted line in graph)
Letopbord.png Cave
  • During this switch ECG monitoring is required because of possible QT-interval prolongation[1][2]
Infobord.png More information
  • Alternatively, first switch to oral form and then switch to depot to manage possible (adverse) reactions. With a direct switch to a depot it is advisable to administer a low testdose in order to exclude adverse reactions.
    Stop28DaysStartDepotRisp.jpg
Nietinrijdenbord.png — Sertindole
Eenrichtingbord.png — Risperidone_LA


  1. SPC Sertindole (Dutch)
  2. SPC Sertindole
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