Fluoxetine-moclobemide

Fluoxetine
Type Antidepressant
Group SSRI
links
Medscape Fluoxetine
PubChem 3386
PubMed Fluoxetine
Kompas (Dutch) Fluoxetine
Wikipedia Fluoxetine
Moclobemide
Type Antidepressant
Group MAO-I
links
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide

Switch medication from fluoxetine to moclobemide.

Nietinrijdenbord.png Stop fluoxetine
  • Decrease with about 25% of original dose every 3 days
  • wait for 5-6 weeks for washout
Eenrichtingbord.png Start moclobemide
  • Start at the first day after the washout period of 5-6 weeks with about 25% of target dose.
Letopbord.png Cave
  • Occurrence of serotonin syndrome is reported when a wash-out period (of four weeks) is not considered.
Infobord.png More information
  • The pharmacologically active metabolite norfluoxetine has a half-life of about 2 weeks.
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