Switch medication from venlafaxine to trazodone.
Before day 1: gradually reduce dosage of venlafaxine to a maximum of 75 mg/ day.
Day 1: reduce a dosage of 75 mg/day to 37,5 mg/day or 75 mg slow release.
Day 8: stop administration of venlafaxine.
Day 9: start trazodone in dosage of 100-150 mg/day.
- If necessary, increase the dosage of trazodone every 3-4 days with 50 mg to a maximum of 400 mg/day.
- Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
The editors of psychiatrienet.nl take the greatest care to provide up-to-date and accurate information on this site. Nevertheless, mistakes and omissions cannot be entirely excluded. No rights devolve from the information provided. The editors and other providers of information to this site accept no responsibility for the content of this site or for the information provided therein; neither do they accept responsibility for possible damages which may derive from the use of the information on this site or from the linked sites. The editorial board accepts no responsibility for the content of the (linked) sites, for access to them, or for the products and services on these sites, nor for the occurrence of errors, viruses, and/or disruptions in service.