Combining-Gabapentin-Lithium

Gabapentin
Type moodstabilizer
Group anticonvulsant
links
ATC-code N03AX12
PubChem 3446
PubMed Gabapentin
Drugs.com gabapentin
Kompas (Dutch) Gabapentin
Wikipedia Gabapentin
Lithium
Type moodstabilizer
Group other
links
ATC-code N05AN01
Medscape Lithium
PubChem 11125
PubMed Lithium
Drugs.com lithium
Kompas (Dutch) Lithium
Wikipedia Lithium

Adding lithium to gabapentin.

Infobord.png General information
  • Gabapentin is eliminated unchanged by the kidney for 100%.
  • Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
  • The advantages of gabapentin include the lack of interactions with other drugs in the cytochrome P450 system and the lack of protein binding. Since there is little risk of drug interactions, use with lithium is likely to be safe. [1]
Eenrichtingbord.png Start lithium
  • Start lithium according to the general dosing advice.
Letopbord.png Cave
  • Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. [2]


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